CSF1R 抗体 (AA 20-514)
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北京 101111
Quick Overview for CSF1R 抗体 (AA 20-514) (ABIN7092907)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-514
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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免疫原
- Recombinant human CSF1R (Ile20-Leu514) (ABIN6961125) produced by using human HEK293 cells
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亚型
- IgG
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应用备注
- ELISA 1/5000-10000,Flow Cyt 1/100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with deionized water
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CSF1R
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背景
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Synonyms:CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Description:The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. -
分子量
- 55.6 kDa
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基因ID
- 1436
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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