NRF2 抗体 (pSer40) (HRP)
Quick Overview for NRF2 抗体 (pSer40) (HRP) (ABIN7091981)
抗原
See all NRF2 (NFE2L2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer40
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Dog,Cow,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human phospho-Nrf2 (Ser40)
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
-
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
-
别名
- Nrf2
-
背景
-
Synonyms: Nrf2 (phospho S40), p-Nrf2 (phospho S40), Nuclear factor-E2 related factor2, HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, Nrf 2, Nuclear factor erythroid 2 related factor 2, Nuclear factor erythroid derived 2 like 2, NF2L2_HUMAN.
Background: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
-
基因ID
- 4780
-
UniProt
- Q16236
-
途径
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
抗原
-