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NRF2 抗体 (AA 366-605)

NFE2L2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3021832
发货至: 中国
  • 抗原 See all NRF2 (NFE2L2) 抗体
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    抗原表位
    • 23
    • 15
    • 9
    • 8
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-605
    适用
    • 121
    • 57
    • 55
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 114
    • 9
    • 1
    克隆类型
    • 104
    • 20
    多克隆
    标记
    • 59
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NRF2 antibody is un-conjugated
    应用范围
    • 97
    • 52
    • 31
    • 29
    • 21
    • 18
    • 15
    • 15
    • 14
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    序列
    YGDTLLGLSD SEVEELDSAP GSVKQNGPKT PVHSSGDMVQ PLSPSQGQST HVHDAQCENT PEKELPVSPG HRKTPFTKDK HSSRLEAHLT RDELRAKALH IPFPVEKIIN LPVVDFNEMM SKEQFNEAQL ALIRDIRRRG KNKVAAQNCR KRKLENIVEL EQDLDHLKDE KEKLLKEKGE NDKSLHLLKK QLSTLYLEVF SMLRDEDGKP YSPSEYSLQQ TRDGNVFLVP KSKKPDVKKN
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 366-605 of human NRF2 (NP_006155.2).
    亚型
    IgG
    Top Product
    Discover our top product NFE2L2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Meng, Song, Wang, Li, Liu, Cui: "Propofol induces proliferation partially via downregulation of p53 protein and promotes migration via activation of the Nrf2 pathway in human breast cancer cell line MDA-MB-231." in: Oncology reports, Vol. 37, Issue 2, pp. 841-848, (2017) (PubMed).

    Xu, Zhang, Lu, Deng, Zhao, Zhao, Zhao: "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan." in: Molecular neurobiology, Vol. 53, Issue 5, pp. 3494-502, (2016) (PubMed).

  • 抗原
    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
    别名
    NFE2L2 (NFE2L2 产品)
    别名
    Nrf2 antibody, nfe2l2 antibody, wu:fc15g09 antibody, wu:fj67e03 antibody, NF-E2R2 antibody, NRF2 antibody, AI194320 antibody, nuclear factor, erythroid 2-like 2a antibody, nuclear factor, erythroid 2 like 2 S homeolog antibody, nuclear factor, erythroid 2 like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, nuclear factor, erythroid 2-like 2 antibody, nfe2l2a antibody, nfe2l2.S antibody, NFE2L2 antibody, Nfe2l2 antibody
    背景
    This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.,NFE2L2,HEBP1,NRF2,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,Cardiovascular,Heart,Cardiac metabolism,NFE2L2
    分子量
    65 kDa/66 kDa/67 kDa
    基因ID
    4780
    UniProt
    Q16236
    途径
    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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