MBD2 抗体 (AA 10-228)
Quick Overview for MBD2 抗体 (AA 10-228) (ABIN7091410)
抗原
See all MBD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-228
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预测反应
- Human
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免疫原
- Recombinant human MBD2 between 10-228 amino acids.
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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别名
- MBD2
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背景
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Synonyms: Demethylase, DMTase, MBD 2, MBD2_HUMAN, MBD2a, Methyl CpG binding domain protein 2, Methyl CpG binding protein MBD2, Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY CO 41.
Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
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基因ID
- 8932
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UniProt
- Q9UBB5
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途径
- Chromatin Binding
抗原
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