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MBD2 抗体 (AA 10-228)

This anti-MBD2 antibody is a 小鼠 单克隆 antibody detecting MBD2 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7091410
发货至: 中国

Quick Overview for MBD2 抗体 (AA 10-228) (ABIN7091410)

抗原

See all MBD2 抗体
MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

适用

  • 48
  • 24
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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宿主

  • 46
  • 1
  • 1
小鼠

克隆类型

  • 43
  • 5
单克隆

标记

  • 31
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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This MBD2 antibody is un-conjugated

应用范围

  • 41
  • 18
  • 10
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

G7R2
  • 抗原表位

    • 8
    • 7
    • 4
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-228

    预测反应

    Human

    免疫原

    Recombinant human MBD2 between 10-228 amino acids.
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

    别名

    MBD2

    背景

    Synonyms: Demethylase, DMTase, MBD 2, MBD2_HUMAN, MBD2a, Methyl CpG binding domain protein 2, Methyl CpG binding protein MBD2, Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY CO 41.

    Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

    基因ID

    8932

    UniProt

    Q9UBB5

    途径

    Chromatin Binding
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