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alpha Actinin 4 抗体

This 兔 单克隆 antibody specifically detects alpha Actinin 4 in WB, IF, ICC 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7090722
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for alpha Actinin 4 抗体 (ABIN7090722)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

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人, 小鼠

宿主

  • 109
  • 18

克隆类型

  • 76
  • 50
单克隆

标记

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This alpha Actinin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

A12H9
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human alpha Actinin 4

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF()
    ICC 1:100-500

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    alpha Actinin 4

    背景

    Synonyms: actinin 4, Actinin alpha 4, Actinin alpha-4, Alpha-actinin-4, _-Actinin-4, _Actinin-4, actinin4, ACTN 4, ACTN4, ACTN4_HUMAN, DKFZp686K23158, F actin cross linking protein, F-actin cross-linking protein, Focal segmental glomerulosclerosis 1, FSGS 1, FSGS, FSGS1, Non muscle alpha actinin 4, Non-muscle alpha-actinin 4.

    Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008].

    基因ID

    81

    UniProt

    O43707

    途径

    Proton Transport
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