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ADAM17 抗体 (AA 201-300) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-ADAM17 antibody specifically detects ADAM17 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN705673
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ADAM17 抗体 (AA 201-300) (Biotin) (ABIN705673)

抗原

See all ADAM17 抗体
ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

适用

  • 134
  • 61
  • 57
  • 3
  • 3
  • 3
  • 1
人, 大鼠, 小鼠

宿主

  • 99
  • 26
  • 6
  • 5
  • 1
  • 1

克隆类型

  • 81
  • 57
多克隆

标记

  • 66
  • 9
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  • 3
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  • 3
  • 3
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This ADAM17 antibody is conjugated to Biotin

应用范围

  • 96
  • 53
  • 48
  • 23
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  • 17
  • 16
  • 15
  • 15
  • 10
  • 4
  • 3
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ADAM17

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

    别名

    ADAM17

    背景

    Synonyms: CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1, Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, ADAM17

    Background: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.

    基因ID

    6868

    UniProt

    P78536

    途径

    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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