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ADAM17 抗体 (AA 201-300)

Name: ADAM17 抗体 (AA 201-300)
SKU: ABIN705671
Availability: OutOfStock

This anti-ADAM17 antibody is a 兔多克隆 antibody detecting ADAM17 in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 1 publication.

Formalin-fixed and paraffin embedded human placenta labeled with Anti-ADAM17/CD156b Polyclonal Antibody, Unconjugated (ABIN705671) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (ADAM17 抗体 (AA 201-300))

IHC

Mouse thymocytes probed with Rabbit Anti-ADAM17 Polyclonal Antibody, Unconjugated . (ADAM17 抗体 (AA 201-300))

FACS

U937 cells probed with ADAM17 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a PE conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (ADAM17 抗体 (AA 201-300))

FACS

Paraformaldehyde-fixed, paraffin embedded rat kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with ADAM17 Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining. (ADAM17 抗体 (AA 201-300))

IHC (p)

4 images

(1 reference)

产品编号 ABIN705671

发货至: 中国

Datasheet as PDF

Quick Overview for ADAM17 抗体 (AA 201-300) (ABIN705671)

抗原

See all ADAM17 抗体

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This ADAM17 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product ADAM17 Primary Antibody

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AA 201-300

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ADAM17

亚型

IgG
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C7 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) antibody
ADAM17 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
Verified ADAM17 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
KO Validated ADAM17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibody
ADAM17 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc) 宿主: 兔 Monoclonal 9E7 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibody
ADAM17 适用: 人 WB, ELISA, IHC, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (pThr735) antibody
ADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibody
ADAM17 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibody
ADAM17 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 1F6 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Li, Xie, He, Wang, Duan, Yang, Wang: "Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis." in: Gene, Vol. 562, Issue 1, pp. 117-27, (2015) (PubMed).
抗原

ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

别名

ADAM17

背景

Synonyms: CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1, Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, ADAM17
Background: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.

基因ID

6868

UniProt

P78536

途径

Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus