CD73 抗体 (PE)
Quick Overview for CD73 抗体 (PE) (ABIN7077431)
抗原
See all CD73 (NT5E) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD73 PE Antibody
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产品特性
- The clone AD2, a mouse monoclonal antibody recognizes a 70kD glycophosphatidylinositol (GPI)-linked 5'nucleotidase (or 5'-Ecto-nucleotidase) cell surface antigen known as CD73. It is widely expressed on various immune as well as non-immune cells including T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, epithelial cells, etc. CD73 catalyzes the conversion of extracellular nucleosides to adenosine and modulates immune responses. Administration of CD73 inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Pre-B leukemia cell line
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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别名
- CD73
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基因ID
- 4907
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UniProt
- P21589
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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