CCR2 抗体 (iFluor™647)
Quick Overview for CCR2 抗体 (iFluor™647) (ABIN7076997)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD192 iFluor647 Antibody
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产品特性
- The clone 1D9, a mouse monoclonal antibody selectively recognizes C-C chemokine receptor type 2 (CCR2), a cell surface protein known as CD192. It belongs to the beta chemokine receptor family having seven transmembrane (7-TM) G protein-linked receptors. CD192 interacts with its ligands CCL2, CCL8 and CCL16. It is expressed on basophils, monocytes/macrophages, dendritic cells, activated T cells and B cells. CD192 plays an important role in the monocytic infiltration of tissues associated with diseases including atherosclerosis, rheumatoid arthritis, and tumors.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- CCR2 transfected human cell line
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CD192
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基因ID
- 729230
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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