CD45 抗体 (mFluor™450)
Quick Overview for CD45 抗体 (mFluor™450) (ABIN7076605)
抗原
See all CD45 (PTPRC) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD45 mFluor™ 450 Antibody
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产品特性
- The clone F10-89-4, a mouse monoclonal antibody, recognizes a hematopoietic cell surface antigen known as CD45 which is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and basophils in peripheral blood. CD45 has a role in signal transduction, modifying signals from other surface molecules. The CD45 antibody has been reported to react weakly with mature circulating erythrocytes and platelets. The antibody recognizes the human leukocyte common antigen which is found on cells from spleen, lymph nodes, 83 % bone marrow cells, and granulocytes. The antigen recognized by F10-89-4 is a glycoprotein with a molecular weight of 190 kDa to 215 kDa
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human T lymphocytes
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亚型
- IgG2a, kappa
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应用备注
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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别名
- CD45
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基因ID
- 5788
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NCBI登录号
- NM_002838
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UniProt
- P08575
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
抗原
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