ube3a 抗体
Quick Overview for ube3a 抗体 (ABIN7076105)
抗原
See all ube3a 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse UBE3A
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应用备注
- IHC/IF (H,M,R) 1:100-1:500/1:500-1:1300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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别名
- UBE3A
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背景
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins.
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基因ID
- 22215
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NCBI登录号
- NP_035798
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UniProt
- O08759
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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