RAP1 抗体
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北京 101111
Quick Overview for RAP1 抗体 (ABIN7075857)
抗原
See all RAP1 (TERF2IP) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse RAP1
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应用备注
- WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000/1:500-1:3000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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别名
- RAP1
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背景
- Telomeric repeat-binding factor 2-interacting protein 1 acts both as a regulator of telomere function and as a transcription regulator. it is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
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分子量
- 46 kDa
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基因ID
- 57321
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UniProt
- Q91VL8
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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