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CD51 抗体

This anti-CD51 antibody is a 兔 多克隆 antibody detecting CD51 in IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7074314
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD51 抗体 (ABIN7074314)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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  • 84
  • 52
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  • 5
  • 5
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人, 小鼠, 大鼠

宿主

  • 101
  • 50
  • 11

克隆类型

  • 101
  • 60
多克隆

标记

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This CD51 antibody is un-conjugated

应用范围

  • 98
  • 73
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  • 21
  • 15
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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
  • 应用备注

    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    Integrin alpha V

    背景

    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.

    基因ID

    16410

    NCBI登录号

    NP_032428

    UniProt

    P43406

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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