Recombinant CSF1R 抗体
Quick Overview for Recombinant CSF1R 抗体 (ABIN7072608)
抗原
See all CSF1R 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD115/M-CSFR [AFS98], Rabbit IgG, kappa
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特异性
- This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised against CD115.
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亚型
- IgG kappa
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应用备注
- AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4 % paraformaldehyde-fixed and decalcified bones (Dong et al., 2016).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CD115/M-CSFR
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背景
- CSF-1R, Macrophage colony-stimulating factor 1 receptor, Csf1r, CD115, CSF-1 receptor, EC 2.7.10.1, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms
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UniProt
- P09581
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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