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Recombinant CD27 抗体

This anti-CD27 antibody is a 兔 Chimeric antibody detecting CD27 in FACS, IF, IP 和 Act. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7072375
发货至: 中国

Quick Overview for Recombinant CD27 抗体 (ABIN7072375)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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Chimeric

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Activation (Act)

克隆位点

LG-3A10
  • 原理

    Anti-CD27 [LG.3A10], Rabbit IgG, kappa

    特异性

    This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.

    交叉反应

    人, 大鼠

    产品特性

    Original Species of Ab: Hamster, Armenian

    Original Format of Ab: IgG

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant

    亚型

    IgG kappa
  • 应用备注

    This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27

    背景

    TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7

    UniProt

    P41272

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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