Recombinant CD27 抗体
Quick Overview for Recombinant CD27 抗体 (ABIN7072375)
抗原
See all CD27 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD27 [LG.3A10], Rabbit IgG, kappa
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特异性
- This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.
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交叉反应
- 人, 大鼠
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产品特性
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant
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亚型
- IgG kappa
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应用备注
- This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD27 (CD27 Molecule (CD27))
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别名
- CD27
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背景
- TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7
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UniProt
- P41272
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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