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Recombinant CD27 抗体

This anti-CD27 antibody is a 仓鼠 单克隆 antibody detecting CD27 in FACS, IF, IP 和 Act. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7072374
发货至: 中国

Quick Overview for Recombinant CD27 抗体 (ABIN7072374)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Activation (Act)

克隆位点

LG-3A10
  • 原理

    Anti-CD27 [LG.3A10], Hamster (Armenian) IgG, kappa

    特异性

    This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.

    交叉反应

    人, 大鼠

    产品特性

    Original Species of Ab: Hamster, Armenian

    Original Format of Ab: IgG

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant

    亚型

    IgG kappa
  • 应用备注

    This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27

    背景

    TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7

    UniProt

    P41272

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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