S1PR1 抗体 (Extracellular)
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- 抗原 See all S1PR1 抗体
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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抗原表位
- AA 17-30, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S1PR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunochromatography (IC), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 1
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,rat - 13,14 amino acid residues identical
- 产品特性
- Anti-S1PR1 (EDG1) (extracellular) Antibody (ABIN7043771, ABIN7045270 and ABIN7045271)) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize S1PR1 from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: SDYVNYDIIVRHYN(C), corresponding to amino acid residues 17-30 of human S1PR1
- 亚型
- IgG
- Top Product
- Discover our top product S1PR1 Primary Antibody
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anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) antibody
S1PR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibodyS1PR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8E4H5 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 51-150) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 311-382) antibodyS1PR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibodyS1PR1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E3H5 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Ser311) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-382) antibodyS1PR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Internal Region) antibodyS1PR1 适用: 人, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IHC
Negative Control: BLP-SR011
Blocking Peptide: BLP-SR011
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- 别名
- S1PR1 (S1PR1 产品)
- 背景
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Sphingosine 1-phosphate receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, CD363, CHEDG1,Lysophospholipids constitute a group of important lipid mediators, lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (S1P), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin1. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration2. Sphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG), S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8)3.Sphingosine 1-phosphate receptor 1 (S1PR1) is ubiquitously expressed. S1PR1 mRNA is detected in the brain, heart, spleen, liver, lung, thymus, kidney, skeletal muscle and lymphoid tissues4. Knockout of the gene encoding S1PR1 is lethal and therefore makes in vivo studies difficult5.
Alternative names: S1PR1 (EDG1), Sphingosine 1-phosphate receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, CD363, CHEDG1 - 基因ID
- 1901
- NCBI登录号
- NM_001400
- UniProt
- P21453
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2
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