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- 抗原 See all O3FAR1 抗体
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
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抗原表位
- AA 22-36, Extracellular
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This O3FAR1 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 原理
- A Rabbit Polyclonal Antibody to GPR120/FFAR4 Conjugated to the Fluorescent Dye FITC
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat - identical, human - 14,15 amino acid residues identical
- 产品特性
- Anti-GPR120/FFAR4 (extracellular) Antibody (ABIN7043397, ABIN7044281 and ABIN7044282) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot and indirect live cell flow cytometry. It has been designed to recognize FFAR4 from rat, mouse, and human samples. \nAnti-GPR120/FFAR4 (extracellular)-FITC Antibody (ABIN7043397, ABIN7044281 and ABIN7044282)-F) is directly conjugated to fluorescein isothiocyanate (FITC). The antibody can be used in immunofluorescent applications such as direct live cell flow cytometry.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RTHFPFFSDVKGDHR, corresponding to amino acid residues 22-36 of mouse FFAR4
- 亚型
- IgG
- Top Product
- Discover our top product O3FAR1 Primary Antibody
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anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (N-Term) antibody
O3FAR1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) antibodyO3FAR1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 22-36), (Extracellular) antibodyO3FAR1 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (C-Term) antibodyO3FAR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 247-258) antibodyO3FAR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 243-292) antibodyO3FAR1 适用: 人, 小鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyVerified O3FAR1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: N/A
- 说明
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Negative Control: (ABIN7582044)
Blocking Peptide: (ABIN7236163)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
- 别名
- FFAR4 (O3FAR1 产品)
- 背景
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G-protein coupled receptor 120, Free fatty acid receptor 4, FFA4 Receptor, G-protein coupled receptor GT01, Omega-3 fatty acid receptor 1, O3far1,Free fatty acid receptor 4 (FFAR4, GPR120), is a member of the rhodopsin family of 7-transmembrane domain G-protein coupled receptors (GPCRs). GPR120/FFAR4 is activated by long chain fatty acids. The protein is a potential therapeutic target for the treatment of type 2 diabetes mellitus (T2DM). GPR120 is associated to insulin sensitizing, anti-inflammatory, and fat metabolism. Evidence shows that GPR120 may be involved in the development of obesity in mice and humans1-4. GPR120 regulates various physiological processes, including gut hormone secretion, islet function, osteoclastogenesis, anti-inflammation, and adipogenesis2-4.GPR120 binds to omega-3 fatty acids and stabilizes the metabolic homeostasis through a cascade of physiological activities. GPR120 exerts its physiological effects through one of two pathways that involves either Gαq or β-arrestin2,3.GPR120 has been shown to be ubiquitously expressed and is primarily detected in the intestine, adipocytes, and pro-inflammatory macrophages1,2.
Alternative names: GPR120/FFAR4 (extracellular), GPR120, FFA4 Receptor , Free fatty acid receptor 4, Omega-3 fatty acid receptor 1, G-protein coupled receptor 120, G-protein coupled receptor GT01, O3far1 - 基因ID
- 107221
- NCBI登录号
- NM_181745
- UniProt
- Q7TMA4
- 途径
- Hormone Transport
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