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O3FAR1 抗体 (AA 21-120)

O3FAR1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387736
发货至: 中国
  • 抗原 See all O3FAR1 抗体
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    抗原表位
    • 14
    • 11
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 61
    • 37
    • 20
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 61
    • 1
    • 1
    克隆类型
    • 62
    • 1
    多克隆
    标记
    • 29
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This O3FAR1 antibody is un-conjugated
    应用范围
    • 54
    • 30
    • 12
    • 12
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human G protein coupled receptor 120
    亚型
    IgG
    Top Product
    Discover our top product O3FAR1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Meng, Yuan, Zhang, Zhang, Fu, Zhu, Shu, Wang, Gao, Xi, Sun, Zhang, Jiang, Wang: "Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice." in: Biochemical and biophysical research communications, Vol. 491, Issue 1, pp. 192-197, (2017) (PubMed).

  • 抗原
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    别名
    GPR120 (O3FAR1 产品)
    别名
    BMIQ10 antibody, GPR120 antibody, GPR129 antibody, GT01 antibody, O3FAR1 antibody, PGR4 antibody, AI552415 antibody, Gpr120 antibody, Gpr129 antibody, KPG_013 antibody, O3far1 antibody, Pgr4 antibody, free fatty acid receptor 4 antibody, phosphodiesterase 6C antibody, FFAR4 antibody, Ffar4 antibody, PDE6C antibody
    背景

    Synonyms: G protein coupled receptor 120, GPCR GPR120, G protein coupled receptor 129, G protein coupled receptor GT01, G protein coupled receptor PGR 4, G protein coupled receptor PGR4, G-protein coupled receptor 120, G-protein coupled receptor 129, G-protein coupled receptor GT01, G-protein coupled receptor PGR4, GPR 120, GPR 129, GPR120, GPR129, GT01, HGNC:19345, MGC119984, O3FA1_HUMAN, O3FAR1, Omega-3 fatty acid receptor 1, PGR 4, PGR4, GPCR120.

    Background: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

    基因ID
    338557
    UniProt
    Q5NUL3
    途径
    Hormone Transport
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