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- 抗原 See all NPY1R 抗体
- NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
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抗原表位
- AA 237-252
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPY1R antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to Neuropeptide Y1 Receptor
- 特异性
- 3rd intracellular loop
- 交叉反应
- 人, 大鼠
- 预测反应
- Rat,mouse - 14,16 amino acid residues identical
- 产品特性
- Anti-NPY1R Antibody is directed against an intracellular epitope of the human neuopeptide Y1 receptor (NPY1R). Anti-NPY1R Antibody (ABIN7043371, ABIN7044668 and ABIN7044669) can be used in western blot analysis, immunohistochemistry, and immunocytochemical applications. It has been designed to recognize NPY1R from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RLKRRNNMMDKMRDNK, corresponding to amino acid residues 237-252 of human NPY1R
- 亚型
- IgG
- Top Product
- Discover our top product NPY1R Primary Antibody
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anti-Neuropeptide Y Receptor Y1 (NPY1R) (AA 301-382) antibody
NPY1R 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (Middle Region) antibodyNPY1R 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (Extracellular Domain) antibodyNPY1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (AA 1-115) antibodyNPY1R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (AA 180-229) antibodyNPY1R 适用: 人, 小鼠, 大鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (Internal Region) antibodyNPY1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (AA 197-210), (Extracellular) antibodyNPY1R 适用: 小鼠 WB, IHC, IF, LCI, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (Cytoplasmic Domain) antibodyNPY1R 适用: 人, 小鼠, 大鼠, 马, 猴, 犬, 豚鼠, 兔, Bat, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (C-Term) antibodyNPY1R 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y Receptor Y1 (NPY1R) (Internal Region) antibodyNPY1R 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IHC|ICC
Negative Control: (ABIN7236086)
Blocking Peptide: (ABIN7236086)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))
- 别名
- NPY1R (NPY1R 产品)
- 背景
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Neuropeptide Y1 receptor, Neuropeptide Y receptor type 1, NPYR, NPYY1,Neuropeptide Y (NPY) is a 36-amino acid peptide neurotransmitter in the central (CNS) and peripheral nervous systems.1 It belongs to the NPY family, together with the peptide YY (PYY) and the pancreatic polypeptide (PP). NPY is involved in regulation of a broad range of homeostatic functions such as eating behavior, hypertension, and reproduction.2NPY exerts its effects via five receptor subtypes known as the neuropeptide Y receptors (NPYR): Y1 (NPY1R), Y2 (NPY2R), Y4 (NPY4R), Y5 (NPY5R) and Y6 (NPY6R).2 Four of these, Y1, Y2, Y4, and Y5, are expressed in humans.2 The NPY receptors belong to the G protein-coupled receptor superfamily whose members share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.Activation of these receptors by NPY produces effects on [Ca2+]i, adenylate cyclase, and a number of ion channels.3 Based on the high frequency and density of NPY receptors in steroid hormone-producing tumors, the NPY receptors might be of potential use in tumor management.2NPY1R is considered to be a postsynaptic receptor. In the CNS, NPY1Rs are concentrated in the cortical areas of the brain, cerebral cortex, olfactory nucleus, hippocampus, hypothalamic nuclei, and thalamic nuclei.4 In addition, this receptor has a bimodal role in the immune system, serving as a strong negative regulator on T cells as well as a key activator of antigen-presenting cell function.5
Alternative names: NPY1R, Neuropeptide Y1 receptor, Neuropeptide Y receptor type 1, NPYR, NPYY1 - 基因ID
- 4886
- NCBI登录号
- NM_000909
- UniProt
- P25929
- 途径
- Negative Regulation of Hormone Secretion, Feeding Behaviour
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