KISS1R 抗体 (3rd Extracellular Loop)
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Quick Overview for KISS1R 抗体 (3rd Extracellular Loop) (ABIN7043294)
抗原
See all KISS1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 3rd Extracellular Loop, AA 292-305
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原理
- A Rabbit Polyclonal Antibody to Kisspeptin Receptor
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交叉反应
- 人, 大鼠
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预测反应
- mouse - 12,14 amino acid residues identical,Rat - 13
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产品特性
- Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of the human kisspeptin receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R
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亚型
- IgG
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应用备注
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WB: 1:500
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IHC|ICC
Negative Control: (ABIN7235833)
Blocking Peptide: (ABIN7235833)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- KISS1R (KISS1 Receptor (KISS1R))
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别名
- KISS1R
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背景
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Synonyms: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12
Description: The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3
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基因ID
- 84634
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NCBI登录号
- NM_032551
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UniProt
- Q969F8
抗原
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