KISS1R 抗体 (3rd Extracellular Loop) (FITC)
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Quick Overview for KISS1R 抗体 (3rd Extracellular Loop) (FITC) (ABIN7582049)
抗原
See all KISS1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 3rd Extracellular Loop, AA 292-305
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原理
- A Rabbit Polyclonal Antibody to KISS1 Receptor (GPR54) (extracellular) conjugated to the fluorescent dye FITC
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序列
- (C)GSWHPRSYAA YALK
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预测反应
- Rat - 13 out of 14 amino acid residues identical,Mouse - 12 out of 14 amino acid residues identical
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产品特性
- Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of human KISS1 receptor. The antibody can be used in western blot, immunohistochemistry and flow cytometry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples. Anti-KISS1 Receptor (GPR54) (extracellular)-FITC Antibody (ABIN7043294, ABIN7044548 and ABIN7044549-F) is directly conjugated to fluorescein isothiocyanate (FITC) fluorophore. This conjugated antibody has been developed to be used in immunofluorescent applications such as direct flow cytometry and live cell imaging.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R
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亚型
- IgG
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应用备注
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WB: The optimal concentration should be determined by the user
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7582044)
Blocking Peptide: (ABIN7235833)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- KISS1R (KISS1 Receptor (KISS1R))
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别名
- KISS1R
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背景
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Synonyms: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12, G-Protein Coupled Receptor 54
Description: The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3
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基因ID
- 84634
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UniProt
- Q969F8
抗原
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