电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KISS1R 抗体 (AA 121-200)

KISS1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN741180
发货至: 中国
  • 抗原 See all KISS1R 抗体
    KISS1R (KISS1 Receptor (KISS1R))
    抗原表位
    • 12
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-200
    适用
    • 44
    • 22
    • 21
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 1
    克隆类型
    • 49
    • 1
    多克隆
    标记
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KISS1R antibody is un-conjugated
    应用范围
    • 24
    • 14
    • 11
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Sheep,Pig,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human KiSS1 receptor
    亚型
    IgG
    Top Product
    Discover our top product KISS1R Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Luo, Li, Li, Zhang, Zhang: "Leptin/leptinR-kisspeptin/kiss1r-GnRH pathway reacting to regulate puberty onset during negative energy balance." in: Life sciences, Vol. 153, pp. 207-12, (2016) (PubMed).

    Luo, Hou, Yin, Zhang: "Expression of kisspeptin/kiss1r system in developing hypothalamus of female rat and the possible effects on reproduction development and maintenance." in: Journal of the Chinese Medical Association : JCMA, Vol. 79, Issue 10, pp. 546-53, (2016) (PubMed).

  • 抗原
    KISS1R (KISS1 Receptor (KISS1R))
    别名
    Kiss1 Receptor (KISS1R 产品)
    别名
    AXOR12 antibody, CPPB1 antibody, GPR54 antibody, HH8 antibody, HOT7T175 antibody, KISS-1R antibody, Gpr54 antibody, KiSS-1 antibody, gpr54 antibody, gpr54-1 antibody, gpr54a antibody, kiss1r antibody, kiss1rl antibody, kissr2 antibody, si:dkey-31m5.9 antibody, axor12 antibody, kissr1a antibody, KISS1 receptor antibody, KISS1 receptor a antibody, KISS1R antibody, Kiss1r antibody, kiss1ra antibody, kiss1r antibody
    背景

    Synonyms: HH8, CPPB1, GPR54, AXOR12, KISS-1R, HOT7T175, KiSS-1 receptor, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R

    Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

    基因ID
    84634
    UniProt
    Q969F8
You are here:
客服