HRH1 抗体 (Extracellular Loop)
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Quick Overview for HRH1 抗体 (Extracellular Loop) (ABIN7043269)
抗原
See all HRH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-191, Extracellular Loop
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原理
- A Rabbit Polyclonal Antibody to Histamine H1 Receptor
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse, human - 14,16 amino acid residues identical,rat - 15
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产品特性
- Anti-Histamine H1 Receptor/HRH1 (extracellular) Antibody (ABIN7043269, ABIN7044512 and ABIN7044513) is a highly specific antibody directed against an epitope of mouse H1R. The antibody can be used in western blot and live cell flow cytometry applications. It has been designed to recognize H1R from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)REDK(S)ETDFYNVTWFK, corresponding to amino acid residues 176 - 191 of mouse H1 Histamine Receptor
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亚型
- IgG
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anti-Histamine Receptor H1 (HRH1) (AA 211-416) antibody
HRH1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H1 (HRH1) (C-Term) antibodyVerified HRH1 适用: 人, 大鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H1 (HRH1) (Cytoplasmic Domain) antibodyHRH1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H1 (HRH1) (AA 312-414) antibodyHRH1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-Histamine Receptor H1 (HRH1) (Internal Region) antibodyVerified HRH1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H1 (HRH1) (Extracellular Domain) antibodyHRH1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H1 (HRH1) antibodyMicroarray verified HRH1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB551360 unconjugated
anti-Histamine Receptor H1 (HRH1) (3rd Intracellular Loop) antibodyHRH1 适用: 大鼠 WB, IHC, IF, FACS, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:300
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235747)
Blocking Peptide: (ABIN7235747)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- HRH1 (Histamine Receptor H1 (HRH1))
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别名
- HRH1
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背景
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Synonyms: Histamine Receptor H1, H1R
Description: Histamine, acts via distinct histamine H1, H2, H3, and H4 receptors, and regulates various physiological and pathological processes. Hence the activity of Histamine receptors is very crucial. They are members of G-protein coupled receptors superfamily. Thus, have seven transmembrane domains, extracellular N-terminal tail and a cytoplasmic C-terminus1.H1 receptor is excitatory and couples to Gq-type proteins, activating a signaling cascade which eventually leads to an increased cellular concentration of Ca2+ 3.H1 receptor is implicated in type I hypersensitivity allergic reactions caused by numerous allergens1. An allergic reaction occurs when allergens activate mast cells that release histamine, the released histamine binds to H1R and this causes an activation of a cascade that leads to vasodilation and vascular hyper-permeability, resulting in allergic inflammation.H1R is expressed in various tissues throughout body, including the airway, vascular smooth muscle, and brain2. H1R expressed in the brain plays an important role in the regulation of sleep-arousal cycle and memory by binding histamine where it acts as a neurotransmitter1.
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基因ID
- 15465
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NCBI登录号
- NM_000861
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UniProt
- P70174
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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