MAS1 抗体 (AA 212-224)
Quick Overview for MAS1 抗体 (AA 212-224) (ABIN7042921)
抗原
See all MAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 212-224
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原理
- A Guinea Pig Polyclonal Antibody to Angiotensin-(1-7) Mas Receptor
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特异性
- 3rd intracellular loop
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,human - identical
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产品特性
- Guinea pig Anti-Angiotensin-(1-7) Mas Receptor Antibody is directed against an epitope of the rat protein. Guinea pig Anti-Angiotensin-(1-7) Mas Receptor Antibody raised in guinea pig can be used in western blot analysis. It has been designed to recognize Ang-(1-7) Mas receptor from rat, mouse and human samples. The antigen used to immunize guinea pigs is the same as Anti-Angiotensin-(1-7) Mas Receptor Antibody (ABIN7042920, ABIN7043904 and ABIN7043905) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KIRKNTWASHSSK, corresponding to amino acid residues 212-224 of the rat Angiotensin-(1-7) Mas receptor
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亚型
- IgG
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anti-MAS1 Oncogene (MAS1) (AA 285-325) antibody
MAS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 187-236) antibodyMAS1 适用: 人, 小鼠, 大鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Middle Region) antibodyMAS1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 212-224) antibodyKO Validated MAS1 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 246-325) antibodyMAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Cytoplasmic Domain) antibodyMAS1 适用: 人, 小鼠, 大鼠, Cow, Pig, Hamster, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) antibodyMAS1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 144-193) antibodyMAS1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Middle Region) antibodyMAS1 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 51-150) antibodyMAS1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:600
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说明
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Negative Control: (ABIN7234720)
Blocking Peptide: (ABIN7234720)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- MAS1 (MAS1 Oncogene (MAS1))
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别名
- MAS1
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背景
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Proto-oncogene Mas, MAS1,The Angiotensin-(1-7) Mas receptor is the recently identified receptor of the biologically active heptapeptide angiotensin-(1-7).1 Angiotensin (Ang)-(1-7) is a metabolite of the well known peptide hormone Angiotensin (Ang) II, a key component of the renin-angiotensin system (RAS) that has a central role in cardiovascular homeostasis. Considerably interest in Ang-(1-7) and its receptor aroused in the last few years since it became apparent that it can counterbalance most of Ang II effects. Thus Ang-(1-7) has vasodilator and hypotensive effects as well as antiarrhythmic and cardioprotective roles.2, 3 The Ang-(1-7) Mas receptor belongs to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily and was originally described as a protooncogene.Signaling via the Ang-(1-7) Mas receptor is still poorly elucidated however, evidence indicates that the receptor is coupled to a Gq/11 protein that activates phospholipase C (PLC).2,3 The Ang-(1-7) Mas receptor is expressed in several organs including heart, kidney, blood vessels, testis and brain. Studies with Ang-(1-7) Mas receptor knockout mice have demonstrated the key role of this receptor in cardiovascular regulation as well as in the regulation of learning and memory.2
Alternative names: Angiotensin-(1-7) Mas Receptor, Proto-oncogene Mas, MAS1 -
基因ID
- 25153
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NCBI登录号
- NM_000789
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UniProt
- P12526
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途径
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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