MAS1 抗体 (AA 212-224)
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- 抗原 See all MAS1 抗体
- MAS1 (MAS1 Oncogene (MAS1))
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抗原表位
- AA 212-224
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to Angiotensin-(1-7) Mas Receptor
- 特异性
- 3rd intracellular loop
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,human - identical
- 产品特性
- Anti-Angiotensin-(1-7) Mas Receptor Antibody (ABIN7042920, ABIN7043904 and ABIN7043905) is a highly specific antibody designed against an epitope of the rat protein. The antibody can be used in western blot, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize Ang-(1-7) Mas receptor from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 质量等级
- KO Validated
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KIRKNTWASHSSK, corresponding to amino acid residues 212-224 of the rat Angiotensin-(1-7) Mas receptor
- 亚型
- IgG
- Top Product
- Discover our top product MAS1 Primary Antibody
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anti-MAS1 Oncogene (MAS1) (AA 285-325) antibody
MAS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 187-236) antibodyMAS1 适用: 人, 小鼠, 大鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Middle Region) antibodyMAS1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 246-325) antibodyMAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Cytoplasmic Domain) antibodyMAS1 适用: 人, 小鼠, 大鼠, Cow, Pig, Hamster, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) antibodyMAS1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 144-193) antibodyMAS1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (Middle Region) antibodyMAS1 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) (AA 51-150) antibodyMAS1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAS1 Oncogene (MAS1) antibodyMAS1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IHC|ICC|IFC
Negative Control: (ABIN7234720)
Blocking Peptide: (ABIN7234720)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- MAS1 (MAS1 Oncogene (MAS1))
- 别名
- MAS1 (MAS1 产品)
- 背景
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Proto-oncogene Mas, MAS1,The Angiotensin-(1-7) Mas receptor is the recently identified receptor of the biologically active heptapeptide Angiotensin-(1-7).1Angiotensin (Ang)-(1-7) is a metabolite of the well known peptide hormone Angiotensin (Ang) II, a key component of the renin-angiotensin system (RAS) that has a central role in cardiovascular homeostasis.Considerably interest in Ang-(1-7) and its receptor aroused in the last few years since it became apparent that it can counterbalance most of Ang II effects. Thus Ang-(1-7) has vasodilator and hypotensive effects as well as antiarrhythmic and cardioprotective roles.2, 3The Ang-(1-7) Mas receptor belongs to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily and was originally described as a protooncogene.Signaling via the Ang-(1-7) Mas receptor is still poorly elucidated however, evidence indicates that the receptor is coupled to a Gq/11 protein that activates phospholipase C (PLC).2,3The Ang-(1-7) Mas receptor is expressed in several organs including heart, kidney, blood vessels, testis and brain. Studies with Ang-(1-7) Mas receptor knockout mice have demonstrated the key role of this receptor in cardiovascular regulation as well as in the regulation of learning and memory.2
Alternative names: Angiotensin-(1-7) Mas Receptor, Proto-oncogene Mas, MAS1 - 基因ID
- 25153
- NCBI登录号
- NM_002377
- UniProt
- P12526
- 途径
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
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