alpha 1 Adrenergic Receptor 抗体 (Cys176Ser-Mutant, Extracellular)
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- 抗原 See all alpha 1 Adrenergic Receptor (ADRA1A) 抗体
- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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抗原表位
- AA 171-183, Cys176Ser-Mutant, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha 1 Adrenergic Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to ?1A-Adrenergic Receptor
- 特异性
- 2nd extracellular loop
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Human,rat,mouse,bovine - 12,13 amino acid residues identical
- 产品特性
- Anti-alpha1A-Adrenergic Receptor (extracellular) Antibody is directed against an extracellular epitope of the human α1A-adrenergic receptor. Anti-α1A-Adrenergic Receptor (extracellular) Antibody (ABIN7042908, ABIN7043908 and ABIN7043909)) can be used in western blot and immunohistochemistry applications. It has been designed to recognize α1A-adrenoceptor from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: EDETI*SQINEEPG(C), corresponding to amino acid residues 171-183 of human alpha1A-adrenoceptor with replacement of cysteine 176 (C176) with serine (*S)
- 亚型
- IgG
- Top Product
- Discover our top product ADRA1A Primary Antibody
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anti-Adrenoceptor alpha 1A (ADRA1A) antibody
ADRA1A 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 346-475) antibodyADRA1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (Internal Region) antibodyADRA1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 206-270) antibodyADRA1A 适用: 人, 大鼠, 小鼠, Cow, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 6-22) antibodyADRA1A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 1-27) antibodyADRA1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G8 unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (AA 330-466) antibodyADRA1A 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (C-Term) antibodyADRA1A 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adrenoceptor alpha 1A (ADRA1A) (C-Term) antibodyADRA1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-AR015
Blocking Peptide: BLP-AR015
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
- 别名
- ADRA1A (ADRA1A 产品)
- 背景
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Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, α1A-AR, ADRA1A,Adrenergic receptors (also called adrenoceptors) are the receptors for the catecholamines adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions.Adrenergic receptors are members of the G-protein coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.Adrenoceptors are divided into three types: α1, α2 and β adrenoceptors. Each type is further divided into at least three subtypes: α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β3.1,2 They are expressed in nearly all peripheral tissues and in the central nervous system.1,2All α1-adrenoceptors (α1-ARs) activate phospholipases C and A2.3 In addition to mobilizing intracellular calcium, the α1-ARs have also been shown to activate calcium influx via voltage-dependent and -independent calcium channels.4The α1A-ARs have at least nine known alternative spliced isoforms. They are the most abundant adrenergic receptor in the brain, and are considered postsynaptic receptors. α1A-ARs are also expressed in the heart, liver and prostate.
Alternative names: alpha1A-Adrenergic Receptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, alpha1A-AR, ADRA1A - 基因ID
- 148
- NCBI登录号
- NM_033303
- UniProt
- P35348
- 途径
- AMPK Signaling
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