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PRKDC 抗体 (pThr2609) (HRP)

This HRP-conjugated 兔 多克隆 anti-PRKDC antibody specifically detects PRKDC in ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN703384
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PRKDC 抗体 (pThr2609) (HRP) (ABIN703384)

抗原

See all PRKDC 抗体
PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

适用

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人, 小鼠

宿主

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克隆类型

  • 144
  • 56
多克隆

标记

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This PRKDC antibody is conjugated to HRP

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pThr2609

    交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PRKDC around the phosphorylation site of Thr2609

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

    别名

    DNA PK/PRKDC

    背景

    Synonyms: DNA PKcsThr2609, PRKDCphospho T2609, DNA PKcs phospho T2609, p-DNA PKcs phospho T2609, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460, PRKDC, HYRC, HYRC1, Variant, DNAPK, DNAPK catalytic subunit, p350, PRKDC, Protein Kinase DNA Activated Catalytic Polypeptide, XRCC 7, XRCC7, PRKDC_HUMAN.

    Background: DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.

    基因ID

    5591

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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