PRKDC 抗体 (pThr2609) (FITC)
Quick Overview for PRKDC 抗体 (pThr2609) (FITC) (ABIN703382)
抗原
See all PRKDC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr2609
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human PRKDC around the phosphorylation site of Thr2609
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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别名
- DNA PK/PRKDC
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背景
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Synonyms: DNA PKcsThr2609, PRKDCphospho T2609, DNA PKcs phospho T2609, p-DNA PKcs phospho T2609, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460, PRKDC, HYRC, HYRC1, Variant, DNAPK, DNAPK catalytic subunit, p350, PRKDC, Protein Kinase DNA Activated Catalytic Polypeptide, XRCC 7, XRCC7, PRKDC_HUMAN.
Background: DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.
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基因ID
- 5591
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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