ITGA5 抗体
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北京 101111
Quick Overview for ITGA5 抗体 (ABIN7013950)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ms CD49e Purified
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特异性
- The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.
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纯化方法
- Purified by protein-G affinity chromatography.
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免疫原
- C57BL/6 x A/J)F1 murine mast cell line
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亚型
- IgG2a kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- CD49e
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背景
- Integrin alpha 5,CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.,ITGA5, VLA-5 alpha, FNRA
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基因ID
- 16402
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UniProt
- P11688
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途径
- Integrin Complex
抗原
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