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DLL4 抗体 (PE)

DLL4 适用: 人 FACS 宿主: 小鼠 Monoclonal MHD4-46 PE
产品编号 ABIN7013930
发货至: 中国
  • 抗原 See all DLL4 抗体
    DLL4 (delta-Like 4 (DLL4))
    适用
    • 48
    • 36
    • 15
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    • 1
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    宿主
    • 55
    • 13
    • 8
    • 1
    • 1
    小鼠
    克隆类型
    • 57
    • 21
    单克隆
    标记
    • 46
    • 8
    • 3
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    • 2
    • 2
    • 2
    • 2
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    This DLL4 antibody is conjugated to PE
    应用范围
    • 40
    • 28
    • 13
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    recombinant soluble human DLL4
    克隆位点
    MHD4-46
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DLL4 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    DLL4 (delta-Like 4 (DLL4))
    别名
    DLL4 (DLL4 产品)
    别名
    hdelta2 antibody, Delta4 antibody, si:ch211-244p18.5 antibody, zgc:136596 antibody, delta like canonical Notch ligand 4 antibody, delta-like 4 (Drosophila) antibody, DLL4 antibody, Dll4 antibody, dll4 antibody
    背景
    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
    基因ID
    54567
    UniProt
    Q9NR61
    途径
    Notch Signaling
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