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DLL4 抗体 (PE)

This PE-conjugated 小鼠 单克隆 anti-DLL4 antibody (Clone MHD4-46) specifically detects DLL4 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7013930
发货至: 中国
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Quick Overview for DLL4 抗体 (PE) (ABIN7013930)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DLL4 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MHD4-46
  • 原理

    Anti-DLL4 PE

    特异性

    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    recombinant soluble human DLL4

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4

    基因ID

    54567

    UniProt

    Q9NR61

    途径

    Notch Signaling
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