DLL4 抗体 (PE)
Our Local Distributor
北京 101111
Quick Overview for DLL4 抗体 (PE) (ABIN7013930)
抗原
See all DLL4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-DLL4 PE
-
特异性
- The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
-
纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
-
免疫原
- recombinant soluble human DLL4
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
- DLL4 (delta-Like 4 (DLL4))
-
别名
- DLL4
-
背景
- Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
-
基因ID
- 54567
-
UniProt
- Q9NR61
-
途径
- Notch Signaling
抗原
-