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beta Catenin 抗体 (pSer33, pSer37, pThr41)

This anti-beta Catenin antibody is a 兔 多克隆 antibody detecting beta Catenin in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265240
发货至: 中国

Quick Overview for beta Catenin 抗体 (pSer33, pSer37, pThr41) (ABIN7265240)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta Catenin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    pSer33, pSer37, pThr41

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    beta-catenin

    背景

    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

    分子量

    Observed_MW: 85 kDa

    Calculated_MW: 9 kDa/85 kDa

    基因ID

    1499

    UniProt

    P35222

    途径

    Peptide Hormone Metabolism
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