BTK 抗体 (pTyr223)
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北京 101111
Quick Overview for BTK 抗体 (pTyr223) (ABIN7265090)
抗原
See all BTK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr223
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- A synthetic phosphorylated peptide around Y223 of human Btk (NP_000052.1).
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亚型
- IgG
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应用备注
- IF 1:20-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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别名
- Btk
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背景
- The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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基因ID
- 695
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UniProt
- Q06187
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途径
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
抗原
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