BTK 抗体 (AA 209-239)
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- 抗原 See all BTK 抗体
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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抗原表位
- AA 209-239
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BTK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product BTK Primary Antibody
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anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 30-240) antibody
BTK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) antibodyBTK 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 27-55) antibodyBTK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (pSer180) antibodyBTK 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 254-443) antibodyBTK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (Internal Region) antibodyBTK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 206-351) antibodyBTK 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 91-387) antibodyBTK 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) antibodyBTK 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7F12H4 unconjugated
anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (C-Term) antibodyBTK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the BTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the BTK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- 别名
- BTK (BTK 产品)
- 别名
- BTK antibody, atk antibody, bpk antibody, xla antibody, imd1 antibody, agmx1 antibody, psctk1 antibody, AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, PSCTK1 antibody, XLA antibody, AI528679 antibody, xid antibody, Bruton tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, BTK antibody, btk antibody, Btk antibody
- 背景
- BTK plays a crucial role in B-cell ontogeny. This protein transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Defects in BTK are the cause of X-linked agammaglobulinemia type 1 (XLA). XLA is a humoral immunodeficiency disease which results in developmental defects in the maturation pathway of B-cells. Affected boys have normal levels of pre-B-cells in their bone marrow but virtually no circulating mature B-lymphocytes. This results in a lack of immunoglobulins of all classes and leads to recurrent bacterial infections like otitis, conjunctivitis, dermatitis, sinusitis or fatal sepsis or meningitis within the first years of life.
- UniProt
- Q06187
- 途径
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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