SMC1A 抗体 (pSer957)
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北京 101111
Quick Overview for SMC1A 抗体 (pSer957) (ABIN7265084)
抗原
See all SMC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer957
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- A synthetic phosphorylated peptide around S957 of human SMC1A (NP_006297.2).
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亚型
- IgG
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anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibody
KD Validated SMC1A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2670 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8C11 unconjugated Recombinant Antibody
anti-Structural Maintenance of Chromosomes 1A (SMC1A) antibodySMC1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (AA 366-465) antibodySMC1A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人 WB, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (N-Term) antibodySMC1A 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (C-Term) antibodySMC1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibodySMC1A 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IF 1:20-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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别名
- SMC1A
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背景
- Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
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Observed_MW: 160 kDa
Calculated_MW: 143 kDa
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基因ID
- 8243
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UniProt
- Q14683
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途径
- Stem Cell Maintenance
抗原
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