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CHMP4B 抗体

This anti-CHMP4B antibody is a 兔 多克隆 antibody detecting CHMP4B in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7011771
发货至: 中国

Quick Overview for CHMP4B 抗体 (ABIN7011771)

抗原

See all CHMP4B 抗体
CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

适用

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  • 21
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  • 2
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  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 1

克隆类型

  • 38
  • 1
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CHMP4B antibody is un-conjugated

应用范围

  • 15
  • 14
  • 13
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  • 12
  • 8
  • 5
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  • 3
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human CHMP4B (NP_789782.1).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

    别名

    CHMP4B

    背景

    This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

    基因ID

    128866

    UniProt

    Q9H444
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