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PARN 抗体

This anti-PARN antibody is a 兔 多克隆 antibody detecting PARN in WB 和 IF. Suitable for 人.
产品编号 ABIN7262849
发货至: 中国

Quick Overview for PARN 抗体 (ABIN7262849)

抗原

See all PARN 抗体
PARN (Poly A Specific Ribonuclease (PARN))

适用

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宿主

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克隆类型

  • 35
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多克隆

标记

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This PARN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human PARN (NP_002573.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PARN (Poly A Specific Ribonuclease (PARN))

    别名

    PARN

    背景

    The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 73 kDa

    Calculated_MW: 52 kDa/66 kDa/67 kDa/73 kDa

    基因ID

    5073

    UniProt

    O95453
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