SSRP1 抗体
Quick Overview for SSRP1 抗体 (ABIN7262236)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human SSRP1 (NP_003137.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- SSRP1
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背景
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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分子量
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Observed_MW: 98 kDa
Calculated_MW: 81 kDa
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基因ID
- 6749
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UniProt
- Q08945
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途径
- Chromatin Binding
抗原
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