KLRK1 抗体
Quick Overview for KLRK1 抗体 (ABIN7261968)
抗原
See all KLRK1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human KLRK1 (NP_031386.2).
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亚型
- IgG
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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibody
KLRK1 适用: 人, 大鼠 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C9B4 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 121-219) antibodyKLRK1 适用: 小鼠 WB, FACS, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibody (FITC)KLRK1 适用: 人 FACS 宿主: 小鼠 Monoclonal 1D11 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 适用: 人 FACS, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 167-216) antibodyKLRK1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibodyKLRK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 92-216) antibodyKLRK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) antibodyKLRK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 75-215) antibodyKLRK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
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别名
- KLRK1
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背景
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
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分子量
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Observed_MW: 30 kDa
Calculated_MW: 25 kDa
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基因ID
- 22914
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UniProt
- P26718
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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