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BTRC 抗体

This anti-BTRC antibody is a 兔 多克隆 antibody detecting BTRC in IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7009768
发货至: 中国

Quick Overview for BTRC 抗体 (ABIN7009768)

抗原

See all BTRC 抗体
BTRC (beta-Transducin Repeat Containing (BTRC))

适用

  • 41
  • 15
  • 11
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 6

克隆类型

  • 39
  • 6
多克隆

标记

  • 23
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BTRC antibody is un-conjugated

应用范围

  • 26
  • 20
  • 16
  • 13
  • 6
  • 4
  • 3
  • 1
  • 1
Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human BTRC.

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BTRC (beta-Transducin Repeat Containing (BTRC))

    别名

    BTRC

    背景

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

    基因ID

    8945

    UniProt

    Q9Y297

    途径

    Cell Division Cycle, Hedgehog Signaling
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