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CD59 抗体

This anti-CD59 antibody is a 兔 多克隆 antibody detecting CD59 in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7259438
发货至: 中国

Quick Overview for CD59 抗体 (ABIN7259438)

抗原

See all CD59 抗体
CD59

适用

  • 170
  • 16
  • 13
  • 10
  • 5
  • 5
  • 5
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 106
  • 95
  • 8
  • 6

克隆类型

  • 118
  • 94
  • 1
多克隆

标记

  • 106
  • 26
  • 14
  • 13
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD59 antibody is un-conjugated

应用范围

  • 107
  • 97
  • 85
  • 48
  • 46
  • 41
  • 33
  • 24
  • 16
  • 14
  • 13
  • 13
  • 11
  • 11
  • 11
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CD59

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CD59

    别名

    CD59

    背景

    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    基因ID

    966

    UniProt

    P13987

    途径

    Complement System
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