SSRP1 抗体
Quick Overview for SSRP1 抗体 (ABIN7257250)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            产品特性
- Polyclonal Antibody
- 
                                            纯化方法
- Affinity purification
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                                            免疫原
- Recombinant fusion protein of human SSRP1 (NP_003137.1).
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 
                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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                                            别名
- SSRP1
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                                            背景
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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                                            分子量
- 
                        Observed_MW: 85 kDa Calculated_MW: 81 kDa 
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                                            基因ID
- 6749
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                                            UniProt
- Q08945
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                                            途径
- Chromatin Binding
 抗原
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