CASC5 抗体
Quick Overview for CASC5 抗体 (ABIN7256628)
抗原
See all CASC5 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human CASC5 (NP_733468.3).
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亚型
- IgG
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anti-Cancer Susceptibility Candidate 5 (CASC5) (AA 1-300) antibody
CASC5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cancer Susceptibility Candidate 5 (CASC5) (AA 2251-2342) antibodyCASC5 适用: 人, 小鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CASC5 (Cancer Susceptibility Candidate 5 (CASC5))
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别名
- CASC5
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背景
- The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11,15)(q23,q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed.
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分子量
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Observed_MW: 300 kDa
Calculated_MW: 195 kDa/205 kDa/262 kDa/265 kDa
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基因ID
- 57082
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UniProt
- Q8NG31
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途径
- Maintenance of Protein Location, Autophagy
抗原
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