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YBX1 抗体

This anti-YBX1 antibody is a 兔 多克隆 antibody detecting YBX1 in IHC 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7254631
发货至: 中国

Quick Overview for YBX1 抗体 (ABIN7254631)

抗原

See all YBX1 抗体
YBX1 (Y Box Binding Protein 1 (YBX1))

适用

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人, 大鼠, 小鼠

宿主

  • 91
  • 32

克隆类型

  • 82
  • 41
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This YBX1 antibody is un-conjugated

应用范围

  • 83
  • 40
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  • 9
  • 5
  • 5
  • 2
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  • 1
Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human YBX1

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    YBX1 (Y Box Binding Protein 1 (YBX1))

    别名

    YBX1

    背景

    This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

    UniProt

    P67809

    途径

    Regulation of Muscle Cell Differentiation
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