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VRK1 抗体

This anti-VRK1 antibody is a 兔 多克隆 antibody detecting VRK1 in WB, IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7252186
发货至: 中国

Quick Overview for VRK1 抗体 (ABIN7252186)

抗原

See all VRK1 抗体
VRK1 (Vaccinia Related Kinase 1 (VRK1))

适用

  • 50
  • 10
  • 4
人, 小鼠

宿主

  • 42
  • 8

克隆类型

  • 44
  • 6
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VRK1 antibody is un-conjugated

应用范围

  • 42
  • 14
  • 13
  • 13
  • 10
  • 9
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human VRK1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    VRK1 (Vaccinia Related Kinase 1 (VRK1))

    别名

    VRK1

    背景

    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 45 kDa

    UniProt

    Q99986
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