电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Notch1 抗体 (Cleaved-Val1754)

This anti-Notch1 antibody is a 兔 多克隆 antibody detecting Notch1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7251301
发货至: 中国

Quick Overview for Notch1 抗体 (Cleaved-Val1754) (ABIN7251301)

抗原

See all Notch1 (NOTCH1) 抗体
Notch1 (NOTCH1) (Notch 1 (NOTCH1))

适用

  • 126
  • 91
  • 49
  • 10
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 106
  • 42
  • 6
  • 3
  • 2
  • 1

克隆类型

  • 97
  • 59
  • 2
多克隆

标记

  • 80
  • 10
  • 9
  • 8
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Notch1 antibody is un-conjugated

应用范围

  • 107
  • 48
  • 47
  • 42
  • 27
  • 26
  • 25
  • 23
  • 20
  • 10
  • 10
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 16
    • 11
    • 10
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cleaved-Val1754

    产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the Internal region of human Notch 1

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, IHC 1:50-300, IF 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Notch1 (NOTCH1) (Notch 1 (NOTCH1))

    别名

    NOTCH1

    背景

    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

    分子量

    Observed_MW: 110 kDa

    Calculated_MW: 273 kDa

    UniProt

    P46531

    途径

    Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
You are here:
Chat with us!