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JAK3 抗体 (pTyr785)

This 兔 多克隆 anti-JAK3 antibody specifically detects JAK3 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7250815
发货至: 中国
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Quick Overview for JAK3 抗体 (pTyr785) (ABIN7250815)

抗原

See all JAK3 抗体
JAK3 (Janus Kinase 3 (JAK3))

适用

  • 85
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  • 2
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 84
  • 5

克隆类型

  • 63
  • 26
多克隆

标记

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  • 1
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  • 1
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  • 1
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  • 1
  • 1
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This JAK3 antibody is un-conjugated

应用范围

  • 56
  • 27
  • 17
  • 14
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  • 11
  • 11
  • 6
  • 6
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 7
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    • 4
    • 3
    • 3
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    • 2
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    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    pTyr785

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    JAK3 (Janus Kinase 3 (JAK3))

    别名

    JAK3

    背景

    The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

    分子量

    Observed_MW: 125 kDa

    Calculated_MW: 125 kDa

    UniProt

    P52333

    途径

    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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