PRKAA1/PRKAA2 抗体 (pThr172, pThr183)
Quick Overview for PRKAA1/PRKAA2 抗体 (pThr172, pThr183) (ABIN7250794)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr172, pThr183
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human AMPKalpha1/2 around the phosphorylation site of Thr183/172
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亚型
- IgG
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody (Cy7)适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, IF (cc), FACS, IF (p) 宿主: 兔 Polyclonal Cy7
anti-AMPK1/AMPK2 (Catalytic Domain), (N-Term) antibody适用: 人, 小鼠, 大鼠, Drosophila melanogaster, Vertebrate WB, ELISA, IF, IHC (fro), IP 宿主: 小鼠 Monoclonal 84-1 unconjugated
anti-AMPK1/AMPK2 (AA 14-47), (N-Term) antibody适用: 小鼠 WB 宿主: 兔 Polyclonal RB43852 unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibody适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (Center) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pSer172), (pSer183) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRKAA1/PRKAA2 (AMPK1/AMPK2)
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别名
- AMPK alpha1/2
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背景
- AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
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分子量
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Observed_MW: 63 kDa
Calculated_MW: 62 kDa
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UniProt
- Q13131, P54646
抗原
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