XRCC4 抗体
Quick Overview for XRCC4 抗体 (ABIN7250143)
抗原
See all XRCC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Monoclonal Antibody
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纯化方法
- Protein A purification
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免疫原
- Synthetic Peptide
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
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别名
- XRCC4
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背景
- Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
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分子量
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Observed_MW: 38 kDa
Calculated_MW: 38 kDa
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UniProt
- Q13426
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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